Talks about Cannabidiol (CBD) and its therapeutic potentials for various ailments like psychotic disorders, peripheral neuropathy, addiction, anxiety, and chronic pain are widespread. Yet as scientists dig deeper into the interaction of the human body and the CBD, they are discovering that one of its most promising potentials is its ability to treat inflammation.
According to researchers, chronic inflammation is to blame for life-threatening ailments, such as arthritis, Alzheimer’s, cancer, heart disease, diabetes, and even depression.
Researchers, nonetheless, are still uncertain on the origin and treatment of inflammation. Yet this perplexity along with the increasing interest in organic options had researchers snooping about the role of CBD as an anti-inflammatory agent. While it is still not completely verified, these five things are important to know about inflammation and CBD.
Inflammation is not really that bad
Inflammation is actually the response of our immune system to harmful pathogens like bacteria. It takes an important role in the body’s immune health by safeguarding us from toxic chemicals, viruses, bacteria, and fungi, and giving time for our body to repair damaged tissue.
It becomes a problem when acute inflammation becomes chronic. This happens when the cellular battle does not cease even when the bad bacteria is eliminated. Rather, the immune system begins fighting its own cells.
It is difficult to treat chronic Inflammation, yet CBD is a promising treatment option
A body of research focusing on the anti-inflammatory potentials of cannabinoids exerted through various channels is growing. These channels are the same routes triggering inflammation, to begin with, such as the induction of T-cell and production of cytokine.
Considering that cannabinoids have the potential to suppress inflammation via multiple pathways, some researchers believe that CBD can temper disease symptoms, including nausea, and pain.
Cannabinoids, based on a research published in the Future of Medicinal Chemistry, have been found to protect the body from the pathogenesis using induction of several anti-inflammatory pathways. They were tested in various experimental models of hepatitis, rheumatoid arthritis, multiple sclerosis, colitis, and other autoimmune disorders.
Some of the most popular treatments for acute inflammation that directly targets the affected area and is absorbed on site are CBD topicals like soaks, lotions, and gels. Although the pieces of evidence are mostly anecdotal, a lot of advocates have dropped the use of conventional nonsteroidal anti-inflammatory drugs like Advil or naproxen in favor of a more organic option.
Joint Inflammation and Arthritis
Injectable fusion-proteins which control pro-inflammatory cytokines are typically used to treat rheumatoid arthritis, osteoarthritis, and other conditions. This treatment option likewise suppresses other immunological functions aside from being effective in managing inflammation.
A study in 2016 discovered that a daily CBD transdermal application in arthritic rats minimizes immune cell infiltration, joint swelling, and pro-inflammatory markers without side effects.
A study in 2015 which examined CBD’s anti-inflammatory potentials among asthma-induced rats discovered that the active cannabinoid reduces levels of cytokines and concluded that it can be a potential medicine to temper inflammatory response in asthma.
Colitis and Inflammatory Bowel Conditions
A study discovered that several CBD applications in colitis-induced mice boosted particular antimicrobial enzyme activity and decreased colonic inflammation.
According to a study, Cannabinoids, including CBD have the potential to aid in regulating the release of cytokines which can intensify allergic responses. Another research discovered that CBD oil aid in reducing the emergence of acne by hampering the production of cytokine and by regulating the production of sebum.
More research is needed
A lot of what is known about CBD and its potential side effects include CBD trials that do not include humans. Experts are still finding the long-term effects of CBD on fertilization, cell viability, hormone production, and understanding how the compound interacts with other drugs.